As scientists show a link between low Vitamin D and Alzheimer’s, an award-winning writer writes that Vitamin D deficiency is behind the increase in conditions such as MS, diabetes, schizophrenia and asthma
Source: Vitamin D – could it stop ‘modern’ diseases? – Telegraph
A cure for type 1 diabetes could be a step closer after scientists managed to halt the condition in mice for six months thanks to the use of insulin-producing cells that had been generated from human stem cells. Experts from US hospitals and institutions including Harvard University managed to transplant cells into mice, which immediately began producing insulin. The team was also able to show they could prevent the cells being rendered useless by the body’s own immune system, which was effectively “switched off” thanks to scientific work.
Source: Diabetes cure may be step closer, scientists say | Health News | Lifestyle | The Independent
Original post from NBC News
Giving young children doses of insulin to “educate” their immune systems might work to prevent type-1 diabetes, researchers reported on Tuesday.
A very early trial in a few children who have a high genetic risk of diabetes showed some indications that the approach might work, the researchers reported in the Journal of the American Medical Association.
Ezio Bonifacio of Dresden Technical University and colleagues tested 25 children at very high genetic risk for type-1 diabetes — the form that develops in childhood and that’s caused when the body mistakenly attacks and kills the insulin-making cells in the pancreas.
“The mechanism seems to be that the immune system is just not seeing insulin appropriately or enough insulin early in life enough to see that it is part of its own body,” Bonifacio said.
“It just makes sense to try and help the immune system by trying to give insulin to these kids,” he added. “We should be able to tell whether this will work and prevent type-1 diabetes.”
The approach works in mice, but humans are far more complicated.
The team gave oral insulin to 15 children and placebo doses to another 10. “We were giving insulin orally to children who hadn’t started the disease process…like sort of a protective vaccination,” Bonifacio said.
They saw signs that might suggest a healthy immune response to the insulin, Bonifacio and colleagues report. The next step will be a bigger trial in more kids to see if the doses really can prevent the development of diabetes.
Other experts noted it will have to be done with care. There’s a chance that giving insulin to very young children could help diabetes develop, rather than preventing it.
— Maggie Fox………….’